Join Us

The Cancer Dependency Map Project (DepMap), an ambitious collaborative effort launched by the Broad Institute’s Cancer Program, aims to systematically identify the genetic and chemical vulnerabilities across human cancers, along with the specific molecular features that can be used to predict which cancers will respond to a given treatment. Using a host of new technologies like CRISPR-based gene editing, pooled drug screening, and next-generation sequencing, we have deeply characterized over a thousand different cancer models and produced some of the largest cancer datasets in the world, which are now being widely used to identify new vulnerabilities in this devastating disease.

Despite the widespread impact of the DepMap project so far, many unanswered questions and critical challenges remain. Now we are poised to launch an exciting next phase of this effort, leveraging cutting-edge new technologies that can, for example, screen the vast space of perturbation combinations, characterize cellular responses with unprecedented detail and single-cell resolution, and leverage next-generation cancer models. To turn these huge, complex data into progress against cancer, we need computational scientists and software engineers. As a member of our team, you will develop new computational and software tools to empower the whole research community in the battle against cancer.

About the team:

In the Cancer Data Science team we pride ourselves on the quality and rigor of our science, but just as much on our work culture. We believe in a team with a healthy work-life balance and a high degree of psychological safety. We look for candidates with diverse backgrounds, strengths, and perspectives, who are willing to challenge and be challenged. We are also a highly collaborative team, working closely with cancer biologists, experimentalists, project managers, clinicians, and others.